Mural granulosa cell gene expression associated with oocyte developmental competence

Mural granulosa cell gene expression associated with oocyte developmental competence

BACKGROUND Ovarian follicle development is a complex process. Paracrine interactions between somatic and germ cells are critical for normal follicular development and oocyte maturation. Studies have suggested that the health and function of the granulosa and cumulus cells may be reflective of the health status of the enclosed oocyte. The objective of the present study is to assess, using an in ...

Comparative analysis of granulosa cell gene expression in association with oocyte competence in FSH-stimulated Holstein cows.

Ovarian stimulation with exogenous FSH followed by FSH withdrawal or 'coasting' is an effective means of increasing the number of oocytes obtainable for the in vitro production of cattle embryos. However, the quality of the oocytes thus obtained varies considerably from one cow to the next. The aim of the present study was to gain a better understanding of the follicular conditions associated w...

Outer space and oocyte developmental competence.

Gene Expression Mural

The Gene Expression Mural is a tool designed for managing the vast amount of information produced by the rapidly growing field of Bioinformatics. The advantages of this tool are that it not only provides an overview of many experiments for an entire genome, but also promotes discovery with its zooming and navigation capabilities. A “tier array” data structure and an averaging algorithm were imp...

Cumulus cell gene expression is associated with oocyte developmental quality and influenced by patient and treatment characteristics.

BACKGROUND Gene expression of cumulus cells (CC) could predict oocyte developmental quality. Knowledge of the genes involved in determining oocyte quality is scanty. The aim was to correlate clinical and biological characteristics during ovarian stimulation with the expression of 10 selected genes in CC. METHODS Sixty-three ICSI patients were stimulated with GnRH-agonist plus highly purified ...